Sergio Ramos’ penalty after the lively Vinicius Jr was fouled gave the visitors the lead. Karim Benzema doubled their advantage before Mikel Merino’s strike set up a tense finale.
Arkadiusz Milik scored the winning spot-kick after Paulo Dybala had seen his first for Juve saved, before team-mate Danilo blazed the second over.
This followed a hard-fought 0-0 over 90 minutes of few chances, played behind closed doors at the Stadio Olimpico.
It gives Napoli boss Gennaro Gattuso his first major trophy as a manager.
However, for his opposite number Maurizio Sarri it is another lost piece of potential silverware.
Luiz, who came on as a first-half substitute, failed to clear the ball just before half-time and Raheem Sterling fired in City’s opener.
The defender was then sent off after pulling back Riyad Mahrez in the second half to give away a penalty, which Kevin de Bruyne coolly slotted in for City’s second.
Substitute Phil Foden netted a third for the defending champions, capitalizing on a rebound from Sergio Aguero’s strike.
Champions League knockout games will be played in a 12-day condensed tournament in Lisbon in August, UEFA has confirmed.
The eight teams remaining in the competition will take part in a straight knockout tournament between August 12 and 23.
Champions League last-16 ties still to be played
UEFA has announced that the Europa League will resume from in early August, with the last remaining last 16 games will be played on 5 and 6 August.
Uefa said: “A decision will be made in due course on whether these matches for which the first leg has already been played will be staged at the home team’s venue or in Germany.
Europa League last-16 ties still to be played
The Bavarians moved 10 points clear of second-placed Borussia Dortmund, who have three games left to play, and secured an eighth consecutive league crown.
In a rollercoaster season that saw coach Niko Kovac fired in November with Bayern off the top spots and Hansi Flick taking over, Bayern turned it around after the winter break, are unbeaten since and won their last 11 straight league matches.
Arsenal boss Mikel Arteta says he is “pretty positive” about agreeing a new contract with 30-year-old striker Pierre-Emerick Aubameyang.
Aubameyang’s current deal runs out in June 2021, and Arteta says the club have to show him why he should stay.
“He needs to feel valued, he needs to feel he belongs to us and that we want him,” said Arteta.
The Gabon international says whether he signs a new deal is “possibly the most important decision” of his career. The forward has scored 61 goals in 97 appearances for the Gunners since joining from Borussia Dortmund in 2018.
Edinson Cavani and Thiago Silva are set to leave Paris St-Germain this summer after the conclusion of the club’s Champions League campaign in August.
The 33-year-old Cavani is PSG’s record scorer with 200 goals and the 35-year-old Silva is club captain.
“It was a difficult decision to make – they are players who made their mark on the club’s history,” sporting director Leonardo told Le Journal du Dimanche.
“The stories were so beautiful. But, yes, we are coming to the end.”
The Bernabeu stadium is being renovated so Real are playing their remaining home games at the Estadio Alfredo di Stefano at their training ground.
Toni Kroos ensured there was no settling in period, driving in a brilliant goal after just four minutes.
Sergio Ramos and Marcelo scored before half-time in a routine win.
The hosts faded badly in the second half, with Marcelo in particular looking dizzy at one point and needing to take on fluids, and Eibar pulled one back through Pedro Bigas’ fortunate strike.
Leading 1-0 from the first leg, Napoli’s advantage was quickly wiped out when Christian Eriksen scored direct from a corner.
Belgium forward Mertens made it 2-1 on aggregate after an assist from Lorenzo Insigne following a counter-attack. It was his 122nd goal for Napoli, one more than Slovakia’s Marek Hamsik.
Mertens, who is nicknamed ‘Ciro’ by Napoli fans to reflect his longstanding relationship with the club and city of Naples, is now seven goals clear of club legend Diego Maradona,