Marco Silva was drawn against his former side as Everton were handed a home draw against Watford.
There’s also a Midlands derby on the cards as Wolves will make the short trip to Birmingham to face Aston Villa.
Reigning champions Manchester City avoided any of the other top six teams left in the draw when they welcome Southampton to the Etihad later this month.
Burton will be hoping the lights won’t go out at the Pirelli Stadium again when they face another Premier League side in Leicester.
And Crawley Town missed out on the chance of a top-flight opponent after being drawn against Colchester. Oxford United and Sunderland complete the fourth-round set of fixtures.
CARABAO CUP FOURTH ROUND DRAW
Everton vs Watford
Aston Villa vs Wolves
Man City vs Southampton
Burton vs Leicester
Chelsea vs Manchester United
Oxford United vs Sunderland
Liverpool vs Arsenal
Crawley Town vs Colchester
These ties will be played the week beginning October 30/31.