In Turin, Juventus beat an outclassed Celtic side 2-0 on the night and 5-0 on aggregate.
Any hopes that the thousands of Celtic fans in the stadium had of a miracle comeback ended after 24 minutes when Alessandro Matril prodded home a parried Fabio Quagliarella strike.
Gianluigi Buffon showed why he is still rated as one of the best goalkeepers in the world as his quick reactions saw him tip a Kris Commons strike, redirected by Gary Hooper, over his crossbar.
That was the closest Celtic came to scoring and Juve put this game away in the second half when Quagliarella added a second. Andrea Pirlo’s delightful ball into the penalty area found Arturo Vidal who skipped towards Fraser Forster and then unselfishly squared to the Italian international who stabbed the ball into an empty net.
In the night’s other game Paris Saint-Germain and Valencia played out a 1-1 draw in the French capital, which saw the hosts progress to the quarter-finals with a 3-2 win on aggregate.
But, eleven minutes later, Ezequiel Lavezzi clipped home his own rebounded strike, after good work by Kevin Gameiro, to equalise and seal Paris Saint-Germain’s progression into the next round of competition.