Carles Puyol will not be available for Tuesday’s game against Arsenal after he failed to recover from his knee injury.
Puyol has been training with the Barcelona squad, but after he he has been ruled out after feeling pain in his left knee after training today due to the tendonitis he has.
Busquets is expected to drop into central defence and will most likely partner Milito.
Barca will also be without Puyol’s defensive partner Pique for the Champions League tie as he will miss the game due to suspension.